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[DOI] [PubMed] [Google Scholar] Sugimoto T, Muro H, Woo M, Nishida N, Murakami K

Tirzepatide acts on both GLP-1 and GIP receptors, potentially offering greater weight loss and improved blood sugar control

Practical Application Emphasize complete proteins: Fish, poultry, eggs, Greek yogurt Plant protein combinations: Legumes + grains for complete amino acid profile Moderate BCAA intake: Avoid excessive leucine-heavy supplements Distribute protein evenly: 25-30g per meal rather than one large serving Combine protein with fiber to slow amino acid absorption Include omega-3 rich protein sources (fatty fish) when possible Pair protein with polyphenol-rich vegetables Strategy 4: Exercise and DPP-4 Activity The Science: Physical activity influences DPP-4 in complex ways

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GLP-1 increases insulin release, decreases glucagon, slows stomach emptying, and enhances satiety to control blood sugar